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- 4-Fluoro-3-Trifluoromethylphenol
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- 3.5-Bistrifluoromethylbromobenzene
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- 2. 4. 6-Trifluorobenzonitrile
1-Bromo-3,5-dichlorobenzene
Product Name: 1-Bromo-3,5-dichlorobenzene
Chemical Formula: C₆H₃BrCl₂
Synonym: 3,5-Dichlorobromobenzene, 3,5-Dichloro-1-bromobenzene
CAS: 19752-55-7
HS Code: 29039990
Molecular Weight: 225.90
Einecs: 243-270-7
Structural Formula: 
BRIEF DESCRIPTION
1-Bromo-3,5-dichlorobenzene is a white to slightly yellow crystalline solid with high symmetry. It is widely used in the synthesis of dyes, pharmaceuticals, and pesticides.
TECHNICAL INDICATORS
| Items | Result |
| Appearance | White to slightly yellow crystals |
| Density | 1.744 g/cm³ |
| Vapor pressure | 0.0998 mmHg (25°C) |
| Purity (%) | ≥99.5% |
APPLICATIONS
1. Pharmaceutical intermediate: Used in the synthesis of antifungal drugs (e.g., benzene ring analogues of miconazole and econazole) and antiparasitic agents. Example: Ullmann coupling to form a diaryl ether structure for enhanced antifungal activity.
2. Pesticide intermediate: Used to prepare diclosulam‑type herbicides and phenylpyrazole insecticides (e.g., chlorine analogues of fipronil).
3. Dye intermediate: Acts as the diazo component for azo dyes to produce bright yellow to red disperse dyes, such as certain Disperse Yellow series.
4. Flame retardant feedstock: Utilizes bromine‑chlorine synergy; can be used to synthesize bromine‑chlorine flame retardants, e.g., alternatives to tetrabromobisphenol A.
STORAGE CONDITIONS
1. Store in a cool, dry, well‑ventilated area.
2. Keep container tightly closed; store in a cool, dry, ventilated place.
3. Separate from oxidizing agents and combustible materials – do not mix storage.
4. Ventilation systems should be equipped with static electricity grounding.
5. The storage area should be equipped with spill containment and appropriate collection materials.
PACKAGE
1.Tightly sealed container.
2.Other packaging forms available upon request.
CHEMICAL PROPERTIES
Melting point: 73–75°C, boiling point: 232°C (757 mmHg). Solid crystals, soluble in hot ethanol, toluene, and dichloromethane. The bromine atom is more reactive than the chlorine atoms, allowing selective palladium‑catalyzed coupling reactions. Dust is irritating; avoid inhalation during handling.
PICTURE
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