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3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylic acid

Product Name: 3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylic acid
Alias: DFPA
Chemical formula: C6H6F2N2O2
CAS: 176969-34-9
Molecular weight: 176.12
Einecs: 700-093-4
Structural formula: DFPA.jpg

    BRIEF DESCRIPTION

    3-Difluoromethyl-1-methyl-1H-pyrazole-4-carboxylic acid has a density of 1.307 g/cm³, a boiling point of 288.4 °C, a flash point of 128.2 °C, and a vapor pressure of 0.27 Pa (25 °C). 3-Difluoromethyl-1-methyl-1H-pyrazole-4-carboxylic acid can be used to prepare difluoromethylpyrazole carboxamide compounds, which can be used as succinate dehydrogenase inhibitor fungicides. Succinate dehydrogenase inhibitor fungicides are highly effective fungicides with high activity against a wide range of plant pathogenic fungi. They are used for fungal control in various cultivated plants such as cotton, vegetables, barley, corn, rice, soybeans, wheat, and seeds, and have become a hot topic of development for major pesticide companies in recent years.

    TECHNICAL INDICATORS

    Appearance White to off-white solid
    Density 1.307 g/cm3
    Melting point 201-203°C
    Boiling point 288.4℃

    Purpose (USE)

    1. 3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylic acid can be used as a pharmaceutical intermediate, such as for the preparation of 2-hydroxyethyl ester (Ⅳ) of 3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxylic acid.
    2. In the field of pesticides: As a key intermediate of succinate dehydrogenase inhibitors (SDHI) fungicides, it is used to control fungal diseases of crops (such as wheat rust and rice sheath blight), and has the characteristics of low toxicity and high efficiency.

    CHEMICAL PROPERTIES

    1.Solubility: Slightly soluble in water, readily soluble in organic solvents such as methanol and DMSO.
    2.Stability: Must be stored in a sealed container away from light; stable at room temperature.

    Coa indicator

    Project Unit Index
    DFPA % ≥99
    Isomers % ≤0.1
    Any single hybrid % <0.10
    Moisture % <0.10

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