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5-Chloromethyl-2H-1,2,4-triazolin-3-one

Product Name: 5-Chloromethyl-2H-1,2,4-triazolin-3-one

Abbreviation:TMCK

Synonyms: Aprepitant Impurity 51

3-Chloromethyl-1,2,4-triazol-5-one

3-Chloromethyl-1,2,4-triazolin-5-one

3-(chloromethyl)-1H-1,2,4-triazol-5(4H)-one

5-CHLOROMETHYL-2,4-DIHYDRO-[1,2,4]TRIAZOL-3-ONE

5-Chloromethyl-2,4-dihydro-[1,2,4]triazol-3-one

5-Chloromethyl-2,4-Dithydro-[1,2,4]Triazol-3-One

5-(chloromethyl)-1,2-dihydro-3H-1,2,4-triazol-3-one

3-(chloroMethyl)-4,5-dihydro-1H-1,2,4-triazol-5-one

5-(CHLOORMETHYL)-1,2-DIHYDRO-3H-1,2,4-TRIAZOOL-3-ON

CAS : 252742-72-6 _

Molecular formula: C3H4ClN3O

Molecular weight: 133.54

Einecs: 607-678-2

Dangerous goods transport number : UN 3261 8/PG II

Structural formula :5-Chloromethyl-2H-1,2,4-triazolin-3-one.jpg

    BRIEF DESCRIPTION

    5-Chloromethyl-2,4-dihydro[1,2,4]triazol-3-one is an organic synthesis intermediate and pharmaceutical intermediate , which can be used in laboratory research and development synthesis processes and chemical and biological research and development processes.

    TECHNICAL INDICATORS

    Analysis

    Requirement

    Exterior

    White to off-white powder

    content

    More than 98%

    Boiling point(℃)

    426°C at 760mmHg

    Melting point(℃)

    199°C(lit.)

    Liquid density ℃ (kg/m)

    1.837g/cm3

    Flash point(℃)

    211.5°C

    Purpose (USE)

    5-Chloromethyl-2,4-dihydro[1,2,4]triazol-3-one is an organic synthesis intermediate and pharmaceutical intermediate, used in the synthesis of antiemetics aprepitant hydrochloride and fort Sapitant.

    STORAGE CONDITIONS

    Store in a dark, dry and sealed manner in a well-ventilated environment .

    PACKAGE

    25kg/cardboard drum packaging

    CHEMICAL PROPERTIES

    Form : powder to crystal
    Color : White to Almost white
    Appearance: TMCK is a colorless crystalline solid. 
    Solubility: It is almost insoluble in water, but soluble in organic solvents such as ether, chloroform and dimethyl sulfoxide. 
    Stability: TMCK has good chemical stability.
    5-Chloromethyl-2H-1,2,4-triazolin-3-oneatz5-Chloromethyl-2H-1,2,4-triazolin-3-one24rl

    description2

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