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N-Methylcarbonyl-2-Chloroacetamidrazone

Product Name:N-Methylcarbonyl-2-Chloroacetamidrazone

Synonyms:2-(2-Chloro-1-Iminoethyl)Hydrazinecarboxylicacidmethylester;Methyl(Z)-2-Chloro-1-Hydrazinoethylidenecarbamate;(Z)-Methyl2-(1-Amino-2-Chloroethylidene);N-Carbomethoxy-2-Chloroacetamidohydrazone

CAS:155742-64-6

Molecular formula:C4H8ClN3O2

Molecular weight:165.58

Einecs:216-849-7

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Structural formula:detail.jpg

    BRIEF DESCRIPTION

    N- Methylcarbonyl-2-Chloroacetamidrazone product specifications:
    GR: Excellent grade pure. The content of main components is very high and the purity is very high. It is suitable for precise analysis and research work, and some can be used as reference materials.
    AR: Analytically pure. The main component content is very high, the purity is high, and the interfering impurities are very low. It is suitable for industrial analysis and chemical experiments.
    CP: Chemically pure. It has high main component content and high purity, and contains interfering impurities. It is suitable for chemical experiments and synthetic preparations.
    LR: experimental pure. The content of the main ingredients is high, the purity is poor, and the impurity content is not selected. The product is only for scientific research and is only suitable for general chemistry.

    TECHNICAL INDICATORS

    Analysis

    Requirement

    Exterior

    Colorless or light yellow liquid

    Boiling point(℃)

    About 173-174 degrees Celsius

    Melting point(℃)

    63-65 degrees Celsius

    Liquid density ℃ (kg/m)

    1.297 g/cm³

    Purpose (USE)

    Purpose Methyl 2-(2-chloro-1-ethylene)hydrazidecarboxylate is a very important intermediate in the synthesis of aprepitant. Aprepitant (English name aprepitant) is the first neurokinin 1 (NK-1) receptor blocker approved by the US FDA in 2003. It works by interacting with NK-1 receptors (mainly found in the central nervous system). system and its periphery) combine to block the effects of substance P.

    STORAGE CONDITIONS

    Refrigerated at low temperature, protected from light, sealed, and dried
    under inert gas (nitrogen or Argon) at 2-8°C

    PACKAGE

    Product specifications: 20mg/1g/25g/500g, etc., customized packaging according to customer needs.

    CHEMICAL PROPERTIES

    Melting point : >125°C(dec.)
    Density : 1.43
    Solubility : soluble in chloroform (slightly, heating, sonication), DMSO (slightly), methanol (slightly)
    form : solid
    Acidity coefficient (pKa) : 7.62±0.43(Predicted)
    Color : light beige to light beige
    N-Methylcarbonyl-2-Chloroacetamidrazone139N-Methylcarbonyl-2-Chloroacetamidrazone2buw

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