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0102030405
N-Methylcarbonyl-2-Chloroacetamidrazone
BRIEF DESCRIPTION
N- Methylcarbonyl-2-Chloroacetamidrazone product specifications:
GR: Excellent grade pure. The content of main components is very high and the purity is very high. It is suitable for precise analysis and research work, and some can be used as reference materials.
AR: Analytically pure. The main component content is very high, the purity is high, and the interfering impurities are very low. It is suitable for industrial analysis and chemical experiments.
CP: Chemically pure. It has high main component content and high purity, and contains interfering impurities. It is suitable for chemical experiments and synthetic preparations.
LR: experimental pure. The content of the main ingredients is high, the purity is poor, and the impurity content is not selected. The product is only for scientific research and is only suitable for general chemistry.
TECHNICAL INDICATORS
Analysis |
Requirement |
Exterior |
Colorless or light yellow liquid |
Boiling point(℃) |
About 173-174 degrees Celsius |
Melting point(℃) |
63-65 degrees Celsius |
Liquid density ℃ (kg/m) |
1.297 g/cm³ |
Purpose (USE)
Purpose Methyl 2-(2-chloro-1-ethylene)hydrazidecarboxylate is a very important intermediate in the synthesis of aprepitant. Aprepitant (English name aprepitant) is the first neurokinin 1 (NK-1) receptor blocker approved by the US FDA in 2003. It works by interacting with NK-1 receptors (mainly found in the central nervous system). system and its periphery) combine to block the effects of substance P.
STORAGE CONDITIONS
Refrigerated at low temperature, protected from light, sealed, and dried
under inert gas (nitrogen or Argon) at 2-8°C
PACKAGE
Product specifications: 20mg/1g/25g/500g, etc., customized packaging according to customer needs.
CHEMICAL PROPERTIES
Melting point : >125°C(dec.)
Density : 1.43
Solubility : soluble in chloroform (slightly, heating, sonication), DMSO (slightly), methanol (slightly)
form : solid
Acidity coefficient (pKa) : 7.62±0.43(Predicted)
Color : light beige to light beige

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